https://goo.gl/6kqcpB
Question Does antidepressant use increase the risk of incident type 2 diabetes among youths?
Findings In a cohort study of youths insured by Medicaid that included 119 608 youths who initiated antidepressant treatment, the current use of selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors—the most commonly used antidepressant subclass—was associated with an increased risk of incident type 2 diabetes that intensified with increasing duration of use, cumulative dose, and average daily dose.
Meaning The study findings provide an impetus to improve monitoring for benefits vs risks of antidepressant use in pediatric care models and to shed light on the underlying biological mechanism of antidepressant treatment–emergent type 2 diabetes.