http://goo.gl/t4VWKg
Recently, however, investigators at Emory University observed that individuals diagnosed with PTSD, and who happened to also be treated with ARBs or ACE inhibitors, exhibited fewer PTSD-like symptoms.
This led the researchers to investigate the underlying mechanisms using an animal model of PTSD in order to expand upon this clinical finding.
Dr. Paul Marvar, first author and Assistant Professor at The George Washington University, explains their findings, "Our current preclinical results show that the ARB losartan, given acutely or chronically to mice, enhances the extinction of fear memory, a process that is disrupted in individuals with PTSD. Overall these data provide further support that this class of medications may have beneficial effects on fear memory in PTSD patients."
Fear extinction is a process by which a memory associated with fear is gradually 'overwritten' in the brain by a new memory with no such association.