Effect of Perioperative Gabapentin on Postoperative Pain Resolution and Opioid Cessation in a Mixed Surgical Cohort

Gabapentin best-known brand is Neurontin, but the article includes the names of other brands.....

https://goo.gl/W3yEYi

Key Points

Question  What is the effect of perioperative gabapentin on remote pain resolution and opioid cessation after surgery?

Findings  In this randomized clinical trial of 422 patients undergoing a variety of operations, no significant difference was found in time to pain cessation between patients receiving 72 hours of perioperative gabapentin compared with placebo. However, perioperative gabapentin had a significant effect on promoting opioid cessation after surgery.

Meaning  Seventy-two hours of perioperative gabapentin use may promote opioid cessation after surgery and decrease the duration of postoperative opioid use.