I prefer to view "overthinking" as deep assessment of data.......
"It occurred to me that if you happen to have a preponderance of negatively hued self-generated thoughts due to high levels of spontaneous activity in the parts of the medial prefrontal cortex that govern conscious perception of threat and you also have a tendency to switch to panic sooner than average people, due to possessing especially high reactivity in the basolateral nuclei of the amygdale, then that means you can experience intense negative emotions even when there's no threat present," Perkins says. "This could mean that for specific neural reasons, high scorers on neuroticism have a highly active imagination, which acts as a built-in threat generator."
The psychiatric relevance of this theory was highlighted by psychiatrist and coauthor Danilo Arnone, who argued that this novel cognitive model might help to explain the ruminative thinking pattern seen in depressionand is complementary to the already defined role of the subgenual prefrontal cortex in the aetiology of mood dysregulation.