Moderate alcohol consumption linked to brain decline

https://goo.gl/nHxNHL

Alcohol consumption is a recognized global public health issue. According to the World Health Organization (WHO), "5.1 percent of the global burden of disease and injury is attributable to alcohol."

In 2010, the World Health Assembly passed a resolution urging countries to "strengthen national responses to public health problems caused by the harmful use of alcohol."

The U.K. government recently tightened their guidance on alcohol consumption, following new evidence of links to cancer.

They suggest that men and women "are safest not to drink regularly more than 14 units per week, to keep health risks from drinking alcohol to a low level." This is roughly the amount of alcohol contained in four pints of strong beer or five large glasses of 14 percent wine.

In their study paper, in which they discuss the rationale for their investigation, the researchers explain that a link between heavy drinking and adverse brain health - including dementia and degeneration of brain tissue - has already been well established.

However, fewer studies have examined the relationship between moderate drinking and brain health, and their evidence is largely inconsistent.

Therefore, the team decided to investigate whether or not there is a link between moderate alcohol consumption and brain changes by analyzing 30 years worth of data (collected between 1985 and 2015) on 550 healthy men and women who took part in the Whitehall II Study.

The participants were aged 43 on average when they started the study and none of them were alcohol dependent.

The data included information about weekly alcohol consumption and regular measures of brain function and mental performance. The participants also had an MRI brain scan at the end of the study.

When they analyzed the data, the researchers found that higher alcohol intake over the 30-year study period was tied to a higher risk of atrophy or tissue degeneration in the hippocampus, which is a part of the brain that is important for spatial orientation and memory.