Brain imaging has shown that people with Fibromyalgia demonstrate very different brains to their counterparts in age and sex who do not have the condition. The systems responsible for experiencing pain in the brain are active and dysfunctional without any signals being sent to them. What this shows is that the pain is real, but its origin is not located in the limb or area that the damaged tissue is. This is important as now treatment can be focused on the right place.