http://goo.gl/hlnxrZ
The findings have important implications for the persistence of memory in coping with stress and depression. The interaction of positive and negative experiences and their corresponding memories is poorly understood, but the findings open a path to new approaches in mood disorder therapy that might be helpful for patients in the future. The authors say it is too early to conclude whether positive memories in general can mitigate the effects of stressful depression. However, it is clear that DG cells are promising targets for therapeutic approaches to maladaptive mood states.