After a week of resveratrol, researchers measured how much dopamine was released by methamphetamine. Researchers found that resveratrol significantly diminished methamphetamine's ability to increase dopamine levels in the brain. Furthermore, resveratrol diminished methamphetamine's ability to increase activity in mice, a behavior that models the hyperactivity observed in people that use the stimulant.
"People are encouraged by physicians and dieticians to include resveratrol-containing products in their diet and protection against methamphetamine's harmful effects may be an added bonus," Miller said. "Additionally, there are no consistently effective treatments to help people who are dependent on methamphetamine. Our initial research suggests that resveratrol could be included in a treatment regimen for those addicted to methamphetamine and it has potential to decrease the craving and desire for the drug. Resveratrol is found in good, colorful foods, and has few side effects. We all ought to consume resveratrol for good brain health; our research suggests it may also prevent the changes in the brain that occur with the development of drug addiction."