Certainly true for me.
Neuroscientists have found that sleep deprivation amplifies anticipatory anxiety by firing up the brain's amygdala and insular cortex, regions associated with emotional processing. The resulting pattern mimics the abnormal neural activity seen in anxiety disorders. Furthermore, their research suggests that innate worriers - those who are naturally more anxious and therefore more likely to develop a full-blown anxiety disorder - are acutely vulnerable to the impact of insufficient sleep.