Millions of people with severe, treatment-resistant depression could get their lives back by adding an anti-inflammatory drug such as aspirin to their anti-depressant medication, a leading consortium of UK researchers in biological psychiatry, the Psychiatric Research into Inflammation, Immunity and Mood Effects (PRIME), reported at the International Congress of the Royal College of Psychiatrists in Brighton.Dr Carmine Pariante, Reader in Biological Psychiatry at the Institute of Psychiatry, Kings College, London, told the Congress that a series of studies published over the last five years now provides sufficiently clear evidence to justify the use of anti inflammatory drugs alongside antidepressant medication.