These measures do not necessarily indicate misuse, but many states flag these instances for review. Our analysis found that seven out of 10 Medicaid enrollees with an opioid prescription had claims in one or two months during 2012. About half (48 percent) of prescriptions were for short-term use with a day supply of two weeks or less. About one-third of opioid prescriptions were for a month’s supply (22-31 days). Nearly 300,000 enrollees had prescriptions for 12 months. Some individuals with chronic pain may receive prescriptions for a longer period of time, and could thus count towards that number. Of the 6.9 million enrollees with opioid prescriptions in 2012, about 5 percent received prescriptions from five or more prescribers and about 2 percent filled them at five or more pharmacies. About 1 percent of Medicaid opioid users received prescriptions from five or more prescribers and filled prescriptions at five or more pharmacies during the year.
I have always found it interesting that Pharma focuses on developing drugs that are less likely to produce tardive dyskinesia than in developing new drugs that eliminate it in people who already have it.....
Antipsychotic treatment can cause involuntary movements such as lip smacking, tongue protrusions and excessive eye blinking. These movements typically occur after more than 3 months of treatment and are called tardive dyskinesia.
Robert A. Hauser, MD, MBA, professor of neurology at the University of South Florida in Tampa, is the lead author of a study published in the American Journal of Psychiatry that concludes valbenazine administered once daily can significantly reduce tardive dyskinesia in patients with schizophrenia, schizoaffective disorder and mood disorder.
"One approach to managing tardive dyskinesia is to discontinue antipsychotic treatment or reduce the dosage, but these options are not always feasible, because withdrawal can exacerbate tardive dyskinesia symptoms or have a negative impact on psychiatric status. Moreover, tardive dyskinesia symptoms often persist even after discontinuation or dosage reduction," wrote Dr. Hauser, who directs the Parkinson's Disease and Movement Disorders Center at USF.
Valbenazine is a selective vesicular monoamine transporter 2 inhibitor. Two hundred twenty-five people with schizophrenia, schizoaffective disorder or a mood disorder participated in the phase 3 randomized double blind, placebo-controlled trial.
Forty-percent of those who received valbenazine 80mg/day improved by at least 50 percent. That's compared to just 8 percent in the placebo group.
Researchers also determined that valbenazine was well tolerated. Drowsiness, restlessness and dry mouth were reported as adverse effects.
Gathering in the small centre before patrol all of the volunteers grab their necessary gear: the bright yellow vests, plastic gloves and containers to store used needles they find on the street. There’s also bags of apples this night. A volunteer named Bob bought them and everyone fills their pockets with the fruit, a hot commodity on the streets, especially with kids. Sometimes they also have candy to hand out, the volunteers laugh that it’s a favourite of the kids.
One kid runs up with an envelope and whispers to a volunteer, “there are needles inside.” It’s taken some time for the Bear Clan to build this kind of trust. Favel says at first when they started people assumed it would be like most social efforts in this neighbourhood—here one day and then gone the next. Good intentions with little follow through is something they know all too well.
Last fall they were in this same housing complex when a woman came outside screaming, Favel says. Two people had been drinking and got into a fight that escalated quickly when one of them brought out a machete. A guy had his fingers almost completely chopped off.
The Bear Clan Patrol have first-aid training and responded quickly, treating the severed fingers and calling for paramedics. It was because of that response the guy ended up keeping mobile fingers, Favel says.
Last November, many of the Bear Clan Patrol members were trained to administer naloxone, an overdose-reversing drug. Members carry the naloxone kits on patrol but they also work with paramedics if they come across someone who may be overdosing.
She’s damaged, often as a result of sexual assault or other abuse by men. Her life carries with it some kind of Deep Lesson, usually a lesson that a male protagonist needs to learn…The Sexy Tragic Muse fetishizes women’s pain by portraying debilitating mental health disorders filtered dreamily through the male gaze. The trope glamourizes addiction and illnesses like depression, bipolar disorder, and schizophrenia — diseases that are distinctly unglamorous for those of us who live with them. The Sexy Tragic Muse is vulnerable, and her vulnerability is sexualized. Her inability to properly care for herself or make decisions on her own behalf is presented as being part of her appeal.
And she was exactly who, in my teens and early 20s, I thought I wanted to be. And that has made it, as I approach 30, all the more difficult to get better.
When you’ve spent most of your life identifying with and even clinging to the worst of you, the most painful, it makes being well and healthy feel an awful lot like giving up.
“For me, it’s a swinging bed on a screened porch in northwestern Wisconsin,” he said. “You can hear the loons and the wind through the fir trees, and there’s the weight of 10 blankets on top of me because it’s a cold night. We’re trying a bunch of interventions.”
Meanwhile, at the University of California, Berkeley, Matthew P. Walker, a professor of neuroscience and psychology and the director of the Sleep and Neuroimaging Laboratory there, is working on direct current stimulation as a cure for sleeplessness in the aging brain. Dr. Walker is also sifting through the millions of hours of human sleep data he has received from Sense, a delicately lovely polycarbonate globe designed to look like the National Stadium in Beijing that measures air quality and other intangibles in your bedroom, then suggests tweaks to help you sleep better.
“I’ve got a mission,” he said. “I want to reunite humanity with the sleep it is so bereft of.” Sense is the first product made by Hello Inc., a technology company started by James Proud, a British entrepreneur, for which Dr. Walker is the chief scientist.
That’s exciting to me. I am glad to be reminded that there are people out there caring about this population and pursuing their career in this field. Along with that, about 1 in 5 Americans suffer from mental illness in a given year. Let me say that again — About 20% of people will suffer from something like depression, bipolar, or some other mental disorder this next year.
When I read stats like that, I’m astounded. I don’t think people realize how prevalent mental illness is today. There are so many other statistics I could go over that might blow your mind.
Some would include rates like the 26% of homeless adults staying in shelters who suffer from a severe mental illness. Or how about mood disorders like depression or bipolar being the third highest cause of hospitalization in the U.S. for people aged 18–44. Poverty is another close link to mental illness that only perpetuates the stigma attached to these individuals.
Federal health officials recently issued a strong warning to consumers about the risks of combining sedating drugs, like Xanax or Valium, with pain medications like opiates. But the analysis found that people taking opiates were about as likely to be on at least two other drugs as those not taking the strong painkillers.
The findings suggest that regular yoga may be a valuable adjunct to conventional medical therapies for ulcerative colitis.
"Many people use yoga to increase their quality of life. Our study suggests that it might be worthwhile to consider yoga as part of a multimodal integrative approach for treating ulcerative colitis," said Prof. Holger Cramer, lead author of the Alimentary Pharmacology & Therapeutics study.
“Before our study, there were no objective, quantitative measures of mild head injury other than imaging,” says lead investigator Daniel Hanley Jr., M.D., the Legum Professor of Neurological Medicine and director of the Brain Injury Outcomes Program at the Johns Hopkins University School of Medicine. “This work opens up the possibility of diagnosing head injury in a very early and precise way.
“This technology is not meant to replace the CT scan in patients with mild head injury, but it provides the clinician with additional information to facilitate routine clinical decision-making,” says Hanley. “If someone with a mild head injury was evaluated on the sports or battlefield, then this test could assist in the decision of whether or not he or she needs rapid transport to the hospital. Alternatively, if there is an accident with many people injured, medical personnel could use the device to triage which patients would need to have CT scans and who should go first. Those showing a ‘positive’ for brain injury would go first.”