Feeling upset? You probably need more sleep

Sleep is the first pillar of successful recovery...

http://goo.gl/n4xyrN

The new research, led by Prof. Talma Hendler of Tel Aviv University (TAU) in Israel, identifies the neurological mechanism responsible for disturbed emotion regulation and increased anxiety due to lack of sleep.

It also shows how sleep deprivation can affect our ability to regulate emotions and allocate brain resources for cognitive processing.

Researchers kept 18 adults awake all night and had them take two rounds of tests while undergoing brain mapping using functional magnetic resonance imaging (fMRI) and/or an electroencephalogram (EEG).

The first test was taken after a good night's sleep and the second after spending a night awake in the lab.

In the first test, participants had to describe the direction in which small yellow dots moved over distracting images. These images were "positively emotional" (a cat), "negatively emotional" (a mutilated body) or "neutral" (a spoon).

Sleepless night changes emotional perception

After a good night's rest, participants identified the direction of the dots hovering over the neutral images faster and more accurately, and their EEG pointed to differing neurological responses to neutral and emotional distractors.

After a wakeful night, however, they performed badly in both the neutral and the emotional image tests, and their electrical brain responses did not reflect a highly different response to the emotional images, indicating a lower degree of regulatory processing.

Fast facts about sleep

  • 43% of Americans aged 13-64 years say they do not get enough sleep
  • 60% have problems sleeping most nights
  • Most Americans feel that 7.5 hours is an appropriate length of time to sleep.

Learn more about sleep

TAU graduate student Eti Ben-Simon, who conducted the experiment, believes that sleep deprivation may universally impair judgment, but it is more likely that a lack of sleep causes neutral images to provoke an emotional response.

The second test examined concentration levels.

Participants inside an fMRI scanner had to complete a task that demanded their attention to press a key or button, while ignoring distracting background pictures with emotional or neutral content.

This time, researchers measured activity levels in different parts of the brain as participants completed the cognitive task.

After only one night without sleep, participants were distracted by every single image (neutral and emotional), while well-rested participants only found the emotional images distracting.

The effect was indicated by activity change, or what Prof. Hendler calls "a change in the emotional specificity" of the amygdala.

Erasing fear: A one-session treatment for phobia?

http://goo.gl/RSEiyP

In this study, Soeter and Kindt recruited 45 volunteers with spider fear. The participants were randomized to receive a single dose of either propranolol, a beta blocker used to treat high blood pressure and heart conditions, or placebo following brief exposure to a tarantula.

Those who received propranolol displayed drastically reduced avoidance behavior and increased approach behavior, an effect that persisted for one year.

"Here we show for the first time that an amnesic drug given in conjunction with memory reactivation transformed avoidance behavior to approach behavior in people with a real-life spider fear. The new treatment is more like surgery than therapy," said Kindt.

"Currently patients with anxiety disorders and PTSD receive multiple sessions of cognitive behavioral treatment or daily drug intake with a gradual (and often temporary) decline of symptoms," added Kindt. "The proposed revolutionary intervention involves one single, brief intervention that leads to a sudden, substantial and lasting loss of fear."


Still in a Crib, Yet Being Given Antipsychotics

http://goo.gl/gzysRH

“People are doing their very best with the tools available to them,” said Dr. Mary Margaret Gleason, a pediatrician and child psychiatrist at Tulane University School of Medicine. “There’s a sense of desperation with families of children who are suffering, and the tool that most providers have is the prescription pad.”

But Dr. Gleason said that children with ages measured in months had brains whose neurological inner workings were developing too rapidly, and in still unknown ways, to risk using medications that can profoundly influence that growth. She said the medications had never been subject to formal clinical trials in infants and toddlers largely because of those dangers.

“There are not studies,” Dr. Gleason said, “and I’m not pushing for them.”


Adderall Got My Friend Hooked on Meth

https://goo.gl/4lPqTN

She’s also not alone. More than 18 million people are getting Adderall prescriptions — and not for ADHD as the drug was intended, but as a weight loss techniquestudy aid and all manner of uses. It’s gotten so common that pharmacies can’t even keep up with the demand. This is startling considering the mounting evidence that Adderall is basically meth. As far as how it acts in a person’s brain and body, Adderall isn’t just basically meth … it is meth.


No, Suicides Don't Rise During the Holidays

http://goo.gl/l8yQLh

It can be good to remind readers that, though most people feel merry during December, it’s also normal to get depressed during the holidays. What’s terrible and dangerous, though, is telling people—falsely—that suicides spike around this time.

According to the CDC, November and December are the months with the fewest suicides. The overwhelming majority of people who kill themselves are mentally ill. For people who otherwise feel fine year-round, feeling mildly down in December is simply not enough to prompt suicide. The stress we associate with the holiday season isn’t the kind of stress that leads to suicide, as Christine Moutier, a psychiatrist and the chief medical officer with the American Foundation for Suicide Prevention, told NPR. Instead, people are driven to end their lives because of factors like genetics, trauma, mental illness, and access to guns.


Former prisoners benefit from Medicaid

http://goo.gl/ffrRxk

In the past, those being released from jail or prison did not qualify for Medicaid, but now they do. These are mostly men on low incomes.

However, many do not have access to programs that would help them enroll in Medicaid once they are released.

Research shows that access to health services on release leads to greater well-being and a lower risk of committing further crimes.

For former prisoners, the first days and weeks back in the community are crucial. A 2007 study published in the New England Journal of Medicine found that in the 2 weeks after release, the mortality rate among former prisoners was 13 times higher than in the general public, especially from a drug overdose.

Many of those being released have serious health conditions, mental illness or substance abuse problems, and often, when their medication runs out, they commit new crimes that put them back in jail.

Researchers from Johns Hopkins Bloomberg School of Public Health in Baltimore, MD, led by Colleen L. Barry, PhD, investigated programs that help enroll prisoners in Medicaid upon release.

As of January 2015, there were 64 programs - half of them in California. Only 42 of these programs have kept data on the numbers enrolled, but those that have kept count had enrolled 112,000 people by January 2015, mostly men. The total number is probably far higher.

Barry explains that men with serious health conditions, from schizophrenia to heart disease, receive treatment while in prison, but leave with 1-2 weeks' supply of medication and no access to a doctor.

Now, in participating states, many newly released prisoners are qualifying for health insurance through Medicaid. A small number of innovative programs have been created to help former prisoners enroll in Medicaid and to connect them with health care services.

Under federal law, those serving time cannot receive Medicaid, so that, on being convicted, people lose their benefits but receive treatment from the corrections system. After, it can take months to re-enroll.

One strategy involves states and counties suspending rather than terminating benefits while serving time, so that Medicaid is automatically reinstated upon release.


Fighting prescription painkiller abuse among baby boomers

http://goo.gl/1rnJXu

Prescription opioid abuse has reached epidemic proportions, with more than half of patients being treated for chronic pain reportedly misusing their medication at some point.

However, new research led by University at Buffalo psychiatric nursing researcher Yu-Ping Chang found motivational interviewing, a form of behavioral counseling, is an effective tool at curbing the abuse.

Motivational interviewing (MI) is designed to promote a patient's desire to change problem behaviors by expressing empathy for their experiences, using non-confrontational dialogue, and developing discrepancies between actual and desired behavior.

Although MI was developed to treat alcohol abuse, researchers wondered if the intervention also could be effective in treating opioid misuse in older adults.

The researchers examined patients 50 years of age and older who experienced chronic pain and were rated at risk for opioid misuse based on screening tools. The participants underwent MI for one month, which consisted of an in-person meeting followed by weekly phone sessions with counselors, and later received a one month follow-up test.

Before and after the intervention, participants completed screening surveys for risk of opioid misuse, alcohol abuse, levels of motivation, self-efficacy, depression and anxiety, chronic pain intensity and treatment satisfaction.

In addition to reducing the risk for opioid misuse, participants reported an increase in confidence, self-efficacy and motivation to change behavior, and a decline in depression, anxiety and the intensity of chronic pain.


Open Dialogue: The radical new treatment having life-changing effects on people's mental health

http://goo.gl/OL9UJy

Open Dialogue is currently being piloted in four NHS trusts. It could revolutionise mental-health care in the UK, according to its champions, who include Suzanne’s psychiatrist, Russell Razzaque. The North East London Foundation Trust, where he works, has just given the go-ahead for an Open Dialogue-based service for patients referred from anywhere in the country, starting next May. 

Open Dialogue is primarily for people who are suffering a mental-health crisis such as suicide or psychosis – 1.8 million of them in the UK last year. They badly need help: a damning report from the Care Quality Commission in June found that the current system is struggling to cope with mental-health crises, with 42 per cent of patients not getting the help they need. A campaign launched last month calls for an increase in funding for mental-health services and parity with physical health. 

The Open Dialogue approach was first developed in Finland in the 1980s, which at the time had one of the worst incidences of schizophrenia in Europe. There are now well-established services in Berlin and New York, where state investment in four respite centres that practise Open Dialogue has been doubled to $100m (£66m). Services are also springing up in Italy, Poland and Scandinavia.


Study provides new insight to antidepressant's effect on immune system

There is a gradual integration of the operations of the immune system, the biome, and the nervous system....

http://goo.gl/FX4pAZ

The immune systems of people with depression have been found to produce an increased inflammatory response. Thisinflammation can lead to the production of neurotoxic compounds that kill brain cells.

In a negative cycle, depression leads to inflammation in the brain, which further increases the feelings of depression.

Dr. Angelos Halaris, lead author of the study and professor at the Department of Psychiatry and Behavioral Neurosciences of Loyola University Chicago Stritch School of Medicine, wanted to investigate whether SSRIs had an impact on this immune response.

The results of the study showed that the patients treated with escitalopram displayed a significant drop in the levels of two neurotoxic compounds over the course of the trial.

Specifically, 3-hydroxykynurenine fell by almost 70% between weeks 8 and 12, and quinolinic acid dropped by 50% during the first eight weeks. Both substances are implicated in neurotoxicity via immune reactions.

The study, after drop-outs, utilized data from just 20 patients. As a result, the researchers warn, the results must be approached with caution.